Title: LCAM-FEBS  Advanced course “Functional imaging”Date: 9-15 June 2024Location: LCAM-FNWI, -NKI & -AMCContact: Mark HinkPrevious editions: 2015, 2017, 2019, 2022 & In the Footsteps of van Leeuwenhoek (bi-annual)Sponsor:  Federation of European Biochemical Societies (FEBS) Introduction:  The ability of cells to …

FEBS Advanced course “Functional imaging of cellular dynamics”, June 2024 Read more »

The Dutch Research Council (NWO) announced on 20 February that the NL-BioImaging consortium will receive major funding from the National Roadmap programme. The Leeuwenhoek Center for Advanced Microscopy (LCAM), a collaboration between the University of Amsterdam and the Antoni van …

LCAM: NL-BioImaging receives 15 million euros from the NWO National Roadmap programme Read more »

The vacuolar lumen of most plant cells is mildly acidic as compared to the surrounding cytoplasm, which is nearly neutral. In some plant tissues, however, vacuoles are extremely acidic. A few years ago, blue petunia flower mutants failing to hyper-acidify …

Research highlight: Hyperacidification of Citrus fruits by a vacuolar proton-pumping P-ATPase complex Read more »

Pathogens use effector proteins to manipulate their hosts. During infection of tomato the fungus Fusarium oxysporum secretes the effectors Avr2 and Six5. Whereas Avr2 suffices to trigger I-2-mediated cell death in heterologous systems, both effectors are required for I-2-mediated disease …

Research highlight: The Fusarium oxysporum Avr2-Six5 effector pair alters plasmodesmatal exclusion selectivity Read more »

In biological research, fluorescent proteins (FPs) are widely used in fluorescence microscopy. FPs are genetically encoded fluorophores, which are produced by cells after a noninvasive transfection. These proteins are utilized as markers and bio-sensors to study biological processes in living …

Research highlight: Automated lifetime-based screening and characterization of fluorescent proteins Read more »