After years of trying, biologists have succeeded in creating an extremely bright red fluorescent protein in the lab. This is good news for researchers, including cancer and stem cell researchers, who use fluorescent proteins to track essential cellular processes. The …
Research highlight: Bright red fluorescent protein created Read more →
20.05.2016 European life science researchers now have the possibility to use state-of-the-art imaging technologies, which they do not find at their home institutions or among their collaboration partners. All they need to do is to apply to Euro-BioImaging (EuBI) via …
15 December 2015 The van Leeuwenhoek Centre for Advanced Microscopy (LCAM), a collaboration of the Netherlands Cancer Institute, the AMC-UvA and the UvA’s Faculty of Science, is according to Euro-BioImaging one of the leading microscopy centres in Europe. The centre …
The small GTPase RhoA is best known for its ability to remodel the actin cytoskeleton of cells. To study the mechanism underlying the spatiotemporal control of RhoA activity by GEFs, single cell imaging was performed with an improved FRET sensor reporting on the nucleotide loading …
Research highlight: Subcellular location of signaling proteins determines cell shape Read more →
Fluorescence lifetime imaging microscopy (FLIM) can be used to study protein-protein interactions by FRET or to perform lifetime-based multiplexing. Mostly live cell imaging is performed for FLIM imaging, but in combination with (antibody) stainings a fixation step is required. Nevertheless, …
Research highlight: The effect of sample fixation on fluorescence lifetime Read more →
17 February 2015 Giulia De Luca, PhD candidate with the Molecular Cytology group at the Swammerdam Institute of Life Sciences (SILS), won the Upcoming Scientist Award at the Innovation for Health conference held in Amsterdam in February. At the conference …
Giulia De Luca (SILS) wins Upcoming Scientist Award at Innovation for Health 2015 Read more →
Giulia De Luca wins Amsterdam Science & Innovation Award 2014 11 June 2014 Giulia De Luca’s Re-scan Confocal Microscopy (RCM) method won the 2014 edition of the Amsterdam Science & Innovation Award, an annual award in recognition of innovative ideas …
Rescan Confocal Microscopy: Winner of Amsterdam Science & Innovation Award 2014 Read more →
Nikon Instruments Europe has partnered with the University of Amsterdam to open a new Center of Excellence in Super Resolution microscopy development. The opening on 23 October 2012, of the state-of-the-art facility enables research across a broad range of disciplines. …
The application of LCAM (a collaborative microscopy center between SILS-FNWI, AMC and NKI) to become a Euro-BioImaging Flaghship centre for Functional Imaging was awarded with the highest possible ranking. Prof.dr. T.W.J. Gadella (LCAM-FNWI, SILS), dr. K. Jalink (LCAM-NKI) & dr. …
Annexins, found in most eukaryotic species, are cytosolic proteins that are able to bind negatively-charged phospholipids in a calcium-dependent manner. Annexin A4 (AnxA4) has been implicated in diverse cellular processes, including the regulation of exocytosis and ion-transport; however, its precise …